Nothing is Sacred to RSD

Effects of RSD + unprovenmeds and treatment--within 18 months: goregou pearlies, then all this:

Ok, as some may know-like all of ya, my fucking mouth is a damned mess.  Right now only my right thigh is burning.

But I am wondering about the specialist I see.  He said that he isn't aware of dental problems linked with CRPS (as my mouth is a mess-see below), and I hung up, disappointed, but finding it hard to believe that my face had been the once place that was only minorly affected, and had gotten my dentist paid off, then only to have the fillings he's replaced be the only things left standing in my mouth.  I am trying to figure out a way to get my dental work paid for-as in, at this point-I am certain it's a denture issue.  $5000.  Fuck him.  I kept digging.

=======================================================

A memo-CRPS needs to stuff it.

(copy of a note I wrote to a friend)

Hey, sup?  Says I

Certainly not I says JJ.  God, I shoulda seen that I was either already fighting RSD with all the surgeries.

But now it feels like my body is getting kicked in the headd-uh, correction, whole body, as that is what my entire body is doing... what my mind did when I suffered acutely from the bipolar: I am not moody as much any more, even with RSD, I just don't know about pain like this.  My state won't allow any form of ketamine, and I didn't bother spending $60 to  get nasal spray-however, they were happy to make an exception to plan so I could switch to a different, non-oxy medication.

Honestly, (-----), I am going for weed.  Forget pain pills, so we're keeping the small dose of PRN, and the seizure meds.  This other crap isn't helping, save to make me more physically dependant and hate them but depend as time goes  on and on-no!

I don't know how you've done this this long. I have my painful fingers and wheelchair-bound legs-yup, already: irony when what was it, 2 years ago that butthole doctor suggested that I was a dope addict, and now with RSD and the state I live in, and that I went out and failed conventional treatment and went on to spread?  Give me a break!


I am not sure why I am writing you-maybe because the online RSD pages I tried to belong to are total jokes with histrionism and narcissistic energy I have NO use for, and less so in time, further less in energy.  I just don't get why a totally and perfectly healthy person would go looking for a diagnosis of RSD.  Particularly w

I go nuts: I have fibro, and I dedicated a whole section of my own website to it, but so many folks blur the line so badly, its bad.

But, maybe I say hello because one person-idk if you even know her, I met her on Inspire, I can't remember, but even at feeling my worst when the whole RSD started-and I had a Caring Bridge page, and had to move it because her "thunderstorms of lightening and pain," every time in the Guestbook cost me a lot of friends because I didn't say anything, sorta hoping she would sorta stop.  Nope.  I moved it, changing the web address-God! Nope.  And my reaction had people I dearly love thinking

Ah, well, a grandson keeps her busy, I have heard little from her since-I do like chatting 1-1 on the phone with her, she was different there, so I guess we all have a public self and a private self.  And some of us have to do that to preserve our sanity-be it within your family, workplace, hell, between you and the whole God-forsaken world.

RSD one year:

                 JULY      2012                                                                         JULY  2011

 

With Pot-Smokin' Honors to......FEZZ!!!

 

Fezz, ya saved my pot smokin' ass!  These are for you!

Ohhh, CRAPS!!!!!!

UPDATE! Final Progress Report: RSDSA and AMERICAN RSDhope Grant

UPDATE! 
Final Progress Report: RSDSA and AMERICAN RSDhope Grant

Researcher’s Name: Richard G. Boles, M.D.
E-mail Address: rboles@chla.usc.edu
Institution: Childrens Hospital Los Angeles
Project Title: Maternally inherited mitochondrial DNA sequence variants and CRPS-I
Date: June 30, 2010

1. What were the (specific) original objectives of this study?

a. To determine the degree of maternal inheritance in CRPS-I.
b. To determine the prevalence of specific functional-disorder-related mitochondrial DNA (mtDNA) polymorphisms in CRPS-I.

2/3. Which objectives have been accomplished - summarize these accomplishments

a. The manuscript of the case series of 8 children with CRPS-I and maternally inherited mitochondrial dysfunction is now published in Archives of Diseases in Childhood.
b. We have further developed and validated our Quantitative Pedigree Analysis methodology (see previous Progress Report).
c. We have found that the same mtDNA polymorphisms associated with cyclic vomiting syndrome are also associated with CRPS-I and multiple additional functional disorders (see attached manuscripts, including a manuscript submitted to Lancet).
d. Co-enzyme Q10 is effective and well tolerated in the treatment of cyclic vomiting syndrome, (published in BMC Neurology). This suggests that “co-Q” may be helpful in the treatment of CRPS-I, which is indeed my anecdotal clinical observation in several cases, especially combined with mega-dosages of B vitamins and high-dosage amitriptyline.
e. We have preliminary data demonstrating probable maternal inheritance in 9/40 (22%) of CRPS-I cases referred through RSDSA/RSDHope, versus 1/40 (2%) of controls (P = 0.004) (see attached abstract presented at Mitochondria 2009 in the Washington D.C. area).
f. We have data demonstrating an association of mtDNA polymorphism 16519T with CRPS-I cases referred through RSDSA/RSDHope (21/49 = 43% of mtDNA haplogroup H CRPS-I subjects versus in 63/231 = 27% of HgH population controls; P = 0.031; odds ratio 2.0, 95% CI 1.1-3.8) (see attached abstract presented at Mitochondria 2009 in the Washington D.C. area). 16519T is also associated with other functional disorders (see attached manuscripts and published articles) and thus this project provides supporting molecular data that CRPS-I is fundamentally related to the other functional disorders.
g. Clinical data from the CRPS-I cases referred through RSDSA/RSDHope reveals that virtually all subjects suffer from multiple functional disorders in addition to CRPS-I. Many patients suffer from more than ten different functional disorders, frequently including the same as the ones that our group found are associated with 16519T.

4. Which objectives have not been accomplished?

None. However, the clinical data is voluminous and a statistician is still analyzing it to see if any additional findings of the study can be found within.

5. Describe any problems in meeting these objectives

The study was delayed because of personnel issues as discussed in the previous Progress Report.

6. Any budgetary questions

None.

7. Future plans for this project

The attached manuscript was recently submitted to Lancet. Some of the CRPS-I data from this study are included in that manuscript. Recently, the P.I. received a good score on the first submission of an NIH grant application to sequence the full mtDNA in large numbers of subjects with cyclic vomiting syndrome and migraine. If funded, any disease-associated mtDNA sequence variants found as part of that study will be assayed for in the current bank of CRPS-I DNA samples.

Once the clinical data has been fully analyzed, likely a manuscript related to CRPS-I will be drafted for publication. This manuscript will probably focus on the high co-morbid functional disease burden in CRPS-I patients, as well as the finding of probable maternal inheritance in a sizable minority.

8. Publications or scientific presentations resulting from this project

Publications Resulting From This Project:

Boles RG, Kerr JR, Zaki EA, Das K, Biswas S, Gardner A. “Functional” and dysautonomic-related conditions: Are we but blind men feeling different parts of an energy-depleted elephant? Submitted to Lancet.


Related Publications:

Higashimoto T, Baldwin E, Gold JI, Boles RG (2008): Reflex sympathetic dystrophy: Complex regional pain syndrome type I in children with mitochondrial disease and maternal inheritance. Arch Dis Child 93:390-7.

Camilleri M, Carlson P, Zinsmeister AR, McKinzie S, Busciglio I, Burton D, Zaki EA, Boles RG (2009): Mitochondrial DNA Polymorphisms, Functional Gastrointestinal Disorders and Gastrointestinal Motor and Sensory Functions. Am J Physiol - Gastrointest Liver Physiol. Am J Physiol Gastrointest Liver Physiol 296:G510-6.

Zaki EA, Freilinger T, Klopstock T, Baldwin EE, Heisner K, Adams K, Dichgans M, Wagler S, Boles RG (2009): Two Common Mitochondrial DNA Polymorphisms Are Highly Associated With Migraine Headache and Cyclic Vomiting Syndrome. Cephalalgia 29:719-28.

Boles RG, Zaki EA, Lavenbarg T, Hejazi R, Foran P, Freeborn J, Trilokekar S, McCallum R (2009): Are pediatric and adult-onset cyclic vomiting syndrome (CVS) biologically different conditions? Relationship of adult-onset CVS with the migraine and pediatric CVS-associated common mtDNA polymorphisms 16519T and 3010A. Neurogastroenterol Motil. Epub ahead of print.

Boles RG, Lovett-Barr MR, Preston A, Li BU, Adams K (2010): Treatment of cyclic vomiting syndrome with co-enzyme Q10 and amitriptyline, a retrospective study. BMC Neurology 10:10.

9. Statement written for the general public summarizing the highlights of this report The term “functional disorders” refers to conditions that cause symptoms, but no abnormal findings on testing, such as from blood or imaging scans. Examples include migraine, cyclic vomiting syndrome (CVS), chronic fatigue syndrome, fibromyalgia, and irritable bowel, as well as CRPS-I (RDS). The first finding of this RSDSA and RSDHope-funded study is that CRPS-I patients usually suffer from multiple functional disorders, including the ones listed above.Second, in this study the Boles group found that disease is primarily inherited in the mother’s family in 22% of CRPS-I families. Maternal inheritance suggests that the genetic mutation causing disease is encoded on the mitochondrial DNA (mtDNA), because the mtDNA is inherited exclusively from the mother.

Third, in this study the Boles group found that the mtDNA sequence variant called 16519T is common in CRPS-I patients. Previously, they had found that 16519T is common in CVS and in migraine patients. The data implies that 16519 doubles the risk that a person will develop CRPS-I. Overall, their data suggests that a sizable minority of CRPS-I patients have disease in part due to mitochondrial dysfunction (low cellular energy levels), which in turn is in part due to DNA sequences inherited from the mother.

NEUROINFLAMMATORY DISEASE AND CRPS - IS THERE A CONNECTION? A DIFFERENCE?

NEUROINFLAMMATORY DISEASE AND CRPS  -  IS THERE A CONNECTION? A DIFFERENCE?

In a recent conversation between Keith Orsini of the American RSDHope Organization and Jim Broatch of the RSDSA, the topic of Neuroinflammatory disease came up. Many patients were concerned about its' connection with CRPS; what that meant for the future of the disease; and of course how it would impact them personally. Were they going to change the name of the disease yet again? What exactly is Neuroinflammatory Disease? Is anyone investigating the connection?

These are just some of the questions that are floating around the CRPS community right now. Keith and Jim felt it was necessary for American RSDHope and the RSDSA to jointly address the issue, so that there was no confusion.

For the answers, Jim Broatch contacted Dr. Mark Cooper, a noted researcher, who has been studying this very connection, and Jim asked him these questions. This was his quite pointed and succinct reply.

"No move to change the name of CRPS. The evidence is substantial that CRPS is a neuroinflammatory disease. The evidence that CRPS has an autoimmune component is also substantial. However, the link between autoimmune and neuroinflammation needs to further established." Dr Mark Cooper

American RSDHope and the RSDSA wanted to address this issue because it is so important to our community and to help ensure everyone better understands the terminology and where the current research stands. The key statement that Dr Cooper makes there is "No move to change the name of CRPS". That question seemed to be causing the most concern in the community.

Doctor Cooper wrote an excellent article titled "Imaging Neuroinflammation—An Important Advance for Pain Medicine"

In October of last year a workshop was held into this very topic. Here is a link that shows some of the topics and speakers.

This is just one in a series of workshops, more will be held in the future. These workshops are instrumental in this research as they bring together some of the top researchers from around the world in one forum to share ideas, information, and their past, current, and future research in various medical areas with the particular emphasis on helping in the diagnosis and treatment of Neuroinflammatory Disorders. This is not only about CRPS but for once, CRPS will lead the way!

RSDSA and American RSDHope Award Research Grant to the Children's Hospital of Los Angeles

RSDSA and American RSDHope Award Research Grant to the Children's Hospital of Los Angeles

Lynne Orsini, Executive Director of American RSDHope, and James W. Broatch, MSW, executive director of the Reflex Sympathetic Dystrophy Association of America (RSDSA ) awarded a $50,000 research grant to Richard Boles, MD, Director, Center for Metabolic and Mitochondrial Disorders at the Childrens Hospital Los Angeles.

Dr. Boles and his team, Essam A. Zaki, Ph.D. Post-doctoral Student, Erin E. Baldwin, MS Genetic Counselor, and Katherine R. U. Heisner, BS, Research Assistant will study Maternally inherited mitochondrial DNA sequence variants and CRPS-I.

Their hypothesis is that is that a brain/nerve energy deficiency that can be caused by maternally inherited changes in the mtDNA code plays an important role in the development of many functional disorders, including CRPS-I. The team will study up to 300 individuals who have been diagnosed with CRPS-I By a physician or other health care providers.

Dr. Boles explains his interest in this subject: "I am a practicing pediatric geneticist/metabolic specialist, as well as a medical researcher in mitochondrial genetics. In my clinical practice, hundreds of families are followed in which multiple matrilineal relatives suffer from neurological disorders, especially intermittent functional conditions. Our interest in complex regional pain syndrome type 1 (CRPS-I) stems from the observation that, in addition to other functional conditions, 12 of my patients have symptoms that meet all of the international diagnostic criteria for CRPS-I. Examples include a 9-year-old girl with severe pain, allodynia (touch perceived as severe pain), swelling and color change to the whole arm and hand for several weeks following an arm bone fracture, and a 14-year-old girl with a change in sensation and color in a stocking-like distribution, with full disability secondary to allodynia following a fall during gymnastics without noted fracture.

"All of those 12 children meet established clinical criteria for the diagnosis of a mitochondrial disorder, and almost all of the family histories are highly suggestive of maternal inheritance. Beyond these 12 children, many more of my patients with mitochondrial disease from families demonstrating maternal-inheritance have frequent episodes of localized extremity pain that doesn't quite meet the CRPS-I diagnostic criteria. Many of their brothers, sisters and mothers have these episodes of pain as well.

CRPS - RSD LONG-TERM HEALTH STUDY

CRPS - RSD LONG-TERM HEALTH STUDY

NEW STUDY NEEDS PARTICIPANTS

The Reflex Sympathetic Dystrophy Syndrome Association (RSDSA) has launched an Internet-based study entitled: Long-term Health Effects of CRPS: A 20- year Cross-sectional and Longitudinal, Observational Cohort Study, funded by a grant from the Brodsky Family Foundation.

Anyone with the diagnosis of CRPS Types I and II can participate via a link on RSDSA's website, www.rsds.org or from the study website (www.crpssurvey.org). Potential participants, who are not familiar or comfortable with Internet-based communication, can contact the study's Project Manager to obtain paper forms for registration, consent and enrollment. Participation is voluntary and anyone can withdraw from the study whenever they wish.

Participants do not need to submit medical records to register for the study, but we may request medical records to confirm information in the database. All questionnaires and records are confidential and securely held according to HIPAA and WIRB provisions. RSDSA hopes that the new study will attract many more participants who will share their experience with CRPS for the benefit of all.

For questions or additional information, please contact the RSDSA Office toll free: 877-662-7737 or email: info@rsds.org 

Click Here to get started:
RSDSA LONG TERM STUDY

CRPS PATIENTS AND DENTISTRS

CRPS Patients and Dentistry
By Dr. Aldino P. Maggiulli

CRPS usually develops after a traumatic episode. Any body part can be affected but the symptoms are mostly seen on the upper and lower extremities. Victims of an injury may develop a burning sensation or numbness on their extremities. Their pain varies day to day. They may develop problems maneuvering their limbs and have dexterity problems. Some people affected with this syndrome face great challenges while trying to accomplish even routine functions. It is important to share any asset which can provide comfort and consistent results to those who suffer with CRPS. This article shares one such asset which was discovered in a dental setting.

It is apparent that patients with CRPS can't be treated in the usual manner as other dental patients. This was discovered when a patient with CRPS came to my office for routine dental treatment. The patient, who we'll call "Will" to provide confidentially entered my office on June 21, 2002. Will informed me that he bad been suffering with CRPS for the past seven years. He mentioned that he had been involved in a car accident and the symptoms of the disease followed there after.

Will was diagnosed with generalized gum disease and a second appointment was made for him to return for aggressive hygiene therapy. His treatment was initiated on July 22, 2002. Traditional dental anesthesia was given and treatment was delivered to the top right and bottom right gum tissues. Will didn't tolerate the deep cleaning procedure well. He reported feeling fatigue and generalized aches. He still had to return to complete the left sides of his dentition. Will had to be motivated to continue. An agreement was made that his next appointments would be shorter. We would treat only the top left side and on a subsequent appointment treat the remaining bottom left side.

Will reluctantly returned on August 6th. Traditional dental anesthesia was given only to the top left side. The appointment time was cut in half and Will reported feeling a little better than his first visit. He wasn't tired but the aches associated with CRPS persisted. A startling discovery was made on Will's third visit. He reluctantly returned for the remaining bottom left gum treatment. Traditional dental anesthesia was given to the bottom left side. The appointment time was short, unlike his first marathon session treating two upper and lower right areas. This appointment was different in that a second dose of dental anesthesia was given to the patient before the gum treatment ended. Will, for the first time, felt great. The decreased appointment time combined with additional local anesthesia close to the conclusion of his gum treatment made this CRPS patient completely comfortable and report no post-op sensation. It's difficult to conclude any significant treatment protocol by revealing the results of just one CRPS patient. This experience demonstrates that CRPS patients can't be treated like traditional patients.

Thanks to Will's help, the conclusion to draw is that it is best to give CRPS patients short dental appointments. CRPS sufferers tire easily and their symptoms may be exacerbated by lengthy dental procedures. The progression of treatment recorded also shows that two doses of local anesthesia are beneficial; one before treatment and one prior to the conclusion of dental treatment. The two dose application allowed this patient comfortable treatment and no fatigue or generalized ache post operatively. It should be noted that this two dose technique has worked consecutively for Will on multiple appointments since this writing, Will has even had a three unit bridge placed without complications and without increasing the symptoms felt with CRPS.

Updated July 19, 2005

DENTAL CARE AND CHRONIC PAIN

Dental Care and Chronic Pain
By Louis Siegelman, DDS

Many aspects of daily life are a significant challenge for patients dealing with chronic pain conditions like complex regional pain syndrome (CRPS) or fibromyalgia. 

Dentistry can often be an extremely difficult environment with its inherent discomforts. Most dentists provide their care with local anesthesia as the sole means of pain control. Some dentists will also use nitrous oxide, which delivers excellent analgesia, and/or a benzodiazepine, such as diazepam (Valium) or triazolam, for relaxation. A limited number of dentists can provide more advanced multimodal therapy that is within the limits of a dental license. Such dentists may be oral surgeons, dentist anesthesiologists, or others with extensive postdoctoral training in anesthesia and pain control. These dentists with more comprehensive training can provide intravenous sedation for oral surgical, pediatric, or general dental procedures.

A comprehensive evaluation and consultation should be the first step in developing a treatment plan that suits the patient’s needs. A detailed past dental and medical history needs to be reviewed. Co-existing mental health conditions relating to panic and anxiety, depression or posttraumatic stress disorder are considerations. Coordination with other involved healthcare providers, such as pain management doctors, internists, neurologists, and surgeons, may be required. All of this information forms the basis for appropriate dental and anesthetic treatment planning.

Multimodal treatment includes a pain management estrategy for pre-emptive analgesia, intra-operative comfort, physical therapy, and postoperative pain relief. The goal is to cover as many pathways of discomfort for patints during the peri-operative period as is reasonable and indicated for specific patients and procedures. Possibilities include alpha agonists, NMDA receptor antagonists, antihistamines, opiates, acetaminophen, NSAIDs, benzodiazepines, steroids, anti-emetics, local anesthetics, and sedative hypnotics. Common routes of administration may be topical, oral, intravenous, or intramuscular. Skillful use of these medications can provide a patient experience that minimizes pain, swelling, nausea, and anxiety. Talk therapy with the dentist or mental healthcare professional can be instrumental in overcoming obstacles to care.

Many patients with chronic pain face constant suffering and may be unwilling to seek professional care for their dental conditions because of fear of additional pain. They may also expect the same level of anesthesia and pain control available for minor medical procedures in the dental environment. Trained dental providers are available, but it’s important for patients to ask questions like what was the type of training the doctor received, how many patients like your self the doctor sees, and how often he/she does these procedures? Many offices and programs offer information online about their services, and treatment philosophy. Calling the office and asking questions of the dental team members is a great way to see if a doctor will be best able to serve a your individual needs.

Louis Siegelman, DDS, is a dentist anesthesiologist practicing in New York City.

RSDSA Review. Summer 2009.

Ain't Nothin Big

 Oh, I must have done something verwy baaaaadQQ

It ain't nothing big,
just in and out of the hospital
in a couple days......
Sixteen months later,
I know my life to be nothing
other than to feel intense, wicked pain

You're up for days
like a "Cowboy...."

I am your mother/father

a treasured brother/sister,

a loved aunt/uncle,

your niece/nephew,

cousin, and anyone else you love and care about!!!

I can be a (or your) doctor, lawyer,

fireman, paramedic, paralegal,

secretary, receptionist, next door

neighbor.  Your family friend.  A member

or several members of your church.

I can be a minister, a psychologist,

a bus driver, a police officer,

the person who delivers your pizza...

IN SHORT--

I can be right here next to you!

and I suffer from RSD/CRPS;

pain knows no boundaries!!!

RSD/CRPS DOESN'T EITHER,

thus far, the most documented severe form

of continuous, unrelenting, undertreated,

least researched cause of "chronic pain."

It is not chronic pain:

It's chronic torture!!!

It is a burning HOT PAIN!!!

Burning, hot, fire,
skin feels scalded down to the wire,
open sores picked at and scrubbed
at with Brillo pads, wire scrub brushes

the slightest breeze,
the smallest bump,
sends the pain into an
unending frenzy of tears,
crying, messy snot and red eyes,
my leg is red and sweaty,
my muscle cramps are unbelieveable....

I feel like I'm shouting into
the wind sometimes
just because this or that symptom isn't
here or there right there right then

Never when they're "testing" for it

I wish like hell you'd leave me alone.....
 I am tired, at age 37,

of feeling like I've been to hell and back,

and back to hell and stayed

longer with each "flare."

I am tired of dreading each flare;

not knowing when it will strike;

only that it will!
would it be my hands resembling claws; 

virtually useless; or totally useless?

Or a leg, shriveled up,

useless, rendering me unable to walk?

Unable to walk, or would it be

unable to hold a fork and feed myself?

Fear the treatment or the disease?

Or my legs?  What happens then?  No, I am not

living in the future, fearing tomorrow;

I have to plan and make sure that I am ready;

ready to kick some ass!

I have already grown tired of the migraines 

the  helllish "syndromes" that grow with you;

I've done nothing to deserve this....

...nothing to put my face on a

"Wanted Poster" that bears either

of these likenessesses on them; and the pain,

The being called a liar,

Looked at I am nuts when I say

I keep the schedule of a cat;
and possess the hearing of a dog........
No longer is a cute baby to behold,

I find them frightening, especially if unprepared

with my trusty earplugs....

I fear they turn into a screaming baby.....
and the agony, horrible burning

pain that goes with it;

screeching, screaming, hollering;

I want to be rescued, I want to be cured;

I want to leave this torture behind...

The swelling, the color changes,

the changes in me-to someone

I don't even recognize, like, and I fight it,

try to smile, and make myself scarce.

But sometimes, it does require an amends.

But see, pain on this scale makes

you feel like you are GOING cray,

not that you are, you reason; you know

you cannot let them win, that in

these days, you have to advoate for yourself

since sure as hell, no one else will!!!

When is the next attack going to hit?

Navy Seal Team 6 gives the fix;

Come on out and kick some ass!

A team that actually

does the job--now can we please

get something done?

You got rid of Osama binLaden

when no one else could;

Can we put you on the job

to help the people suffering

from RSD, chronic, unrelenting pain,

be it from nervous system disorders,

or whatever else-you see gentlemen,

It's being fouled up big time now;

Let's work on it--YOU guys

have a better track record than

what the various governments are

in way of completely screwing it up!

So what--how do I give the order?

Ketamine in Liquid Form-CUT WITH GOD KNOWS WHAT-go legally

Basics

Ketamine, Special K or K, is a fast-acting 'dissociative anesthetic'. Rather than blocking pain like traditional painkillers, it shuts off the brain from the body. With the brain no longer processing information from nerve pathways, awareness expands resulting in a hallucinogenic state.
Since 1970, it has been popular in medicine in the UK and US and all over the world as a safe anesthetic for children and the elderly. Doctors in the Emergency Room may use K for certain procedures, including intubating youngsters.
Special K is also used as a sedative for patients in the Intensive Care ward of the hospital and to treat bronchial spasms. It is also used by vets on animals for short operations, hence it being dubbed a "horse tranquilizer." Find out more about Ketamine's use in medicine here.
Ketamine users tend to be teenagers and young adults. This drug may be bought at dance clubs and raves. According to a survey conducted by the University of Michigan's Monitoring the Future Survey, approximately three percent of high school students had tried K at some point.
Street prices vary, depending on the dealer involved, the quality of the product and the geographic area involved. In some cases, ketamine can be bought for as little as $10 per gram, although some dealers charge between $20-$50 per gram of the drug at parties and special events.

Special K Appearance

Ketamine comes in three main forms: powder, tablet and liquid. The most common form is white powder which is snorted. It looks like cocaine but is smoother and less likely to form hard rocks or a flowery texture if damp.
Most users start out by taking Ketamine in powdered form as it allows them to introduce themselves to the drug with small amounts. When ketamine is being ingested
in this way, the dosage ranges from 15-200 mg.

K in a Tablet Form

Ketamine also appears intermittently in tablet or capsule form, often masquerading as a brand of Ecstasy with the same meaningless "dove" or "Mitsubishi" logos.
Ketamine pills are usually very diluted and cut with a stimulant like ephedrine (a natural amphetamine-like chemical) to produce a mildly trippy speedy effect.
Ketamine sold as Ecstasy may be the origin of the "smacky pills" legend, which contends that pills sold as EX were cut with other substances, such as speed, LSD or other substances. Taking one of them made the user more likely to have an overdose or have an allergic reaction, since the true ingredients of the pill may not be known.

Ketamine in Liquid Form

Ketamine Hydrochloride, intended for use as a hospital anesthetic, is sold in liquid form in small 10 ml bottles, often with the brand names Ketaset, Ketavet and Ketalar.
Some recreational Ketamine users inject this liquid into a muscle. We strongly advise against injecting Ketamine intravenously. You could pass out immediately.
Some people mix Kit Kat with another liquid so that they can consume the mixture as a beverage. Avoid drinking it as well. Liquid ketamine is very hard on the stomach. Profuse vomiting is possible. If you pass out, you may choke on your vomit.
Do not mix Vitamin K with alcohol. Driving while under the influence of ketamine is not a good idea, either. People who choose to use this drug should also avoid activities like swimming or operating heavy equipment.

CK 1

CK 1 is a combination of cocaine or crack cocaine (smokeable cocaine mixed with sodium bicarbonate) and ketamine. The cocaine roots the user in the real world and counters the tendency for higher doses of K to send you into a conscious, paralyzed state.

Sucks to have it-what are people doing stupid crap?

I wonder-why in God's name would anyone or  how, someone could waste away, malnutrition--I'm sorry, but there's no way to fake RSD.  I get bored talking about nothing but getting the grail, ketamine.


Anyhow, I am hurting, in pain, and need to medicate-so here are some videos for your viewing pleasure.

Cheers!

Is there a difference in the 1st 2 vids, and the last 2?

Can Ketamine fix this?

What is RSD?

It is the sleeping hours of a cat,

and the hearing of a dog......only sometimes

A cute, albeit nightmarish hell of a screaming baby

in a store can unleash the torrents of hellish pain,

and in feeling like you've just heard fingernails dragged across a chalkboard.

But can set off your RSD pain...arm, leg, whole body, whatever...

That cute child???

The one everyone, including me,

would love to hold and love, if this thing called pain

is ever to be “brought under control”

as my neurologist, Dr. J says,

so that he can do the proper studies....

pain control exists, I wonder, I think to myself.

I should see that day.

What is RSD?

RSD is an “Odd duck,” even to neurologists,

the very doctors you'd think would treat this....

and some have been unknowingly been outright cruel to RSD patients,

subjecting them to the nerve conduction studies

before achieving enough control to examine them

without causing excruciating pain..

I had a neurologist examine me, causing a cresendo of pain,

I nearly threw up on her shoes,

and I've achieved enough control not to scream,

and she then told me it was a “psychological problem,”

having to do with my “psychological issues,

and refraining also from saying anything “impolite”

I merely took the slip that said I was to make a follow-up,

and threw it away on my way out.

I'm not a sadist. I just have RSD.

She even wrote that it was “neurogenic pain”

due to my “psychological disorder.”

Anyone would have psychological disorders after a screaming exam like that!

But what does RSD feel like??

The sleeping habits of a cat, the hearing of a dog.

I start the month with a large box of ear plugs.....

the only thing that helps the latter.

The skin sensitivity is a killer...the pain will take your breath away,

make you vomit, and when you finish, you want to scream and cry.

The burning pain, the burning, flaming, incinerating, kindling,

roasting, scalding, scorching, smoking, blazing, and finally withering away

of just one part of the body.....my leg was never the same after the surgery.

I feel like acid has been poured on my skin,

but no burn can be seen....

Dousing your leg with lighter fluid, and lighting a match,

leaving the fire to burn, 24/7....

Then, when someone touches me,

it feels like an open wound

being rubbed, scrubbed, and scraped, with sandpaper and wire brushes.

My soft warn blankets bring relief.

the electric on a low setting

No pain when they touch my skin,

and they serve to protect me from the elements

I have an apartment full of medical equipment.

I have not one, but two shower chairs: 

One is a bench, and see below:

age 19

2003

2008

 I want to be optimistic.  If I could say anything to the doctor, this would be it-

To the CEO of Virginia Mason, and gave my doctor a degree, diplom

Life can really suck

This "driver" called a couple times, and he DID NOT show up, and I am low on it-stuff that is any good, and it is a bunch  of shitt=could  not leave a message?  His last call was at 5:45 and he can't leave a fucking message-I called several times since his car supposedly broke down, and until 8, when they put up a closed sign.

RSD SUCKS 1 & 2 AND SO WHAT IF...MAKES IT SUCK JUST A LITTLE LESS

"SO WHAT IF THE THC DOES MAKE IT SUCK LESS"

Now I am alone.

Catholic Community Services pulled my chore volunteer.  I have no help with housework, no help with care-NOTHING.

Talk about screwy!

The MMJ is helping-I know it's easy to say, "But I thought you were doing so well."  But my RSD is full-body and I am always either in my recliner and/or in bed: I don't have restorative therapies available to me and have weakened to the point where I am getting pressure sores-I have had to get a bed-rail so that I can independently get around.  And some days are better than others.  I don't want to stay in one place all the time: I want to be comfortable where I am.  I am doing okay right now-FOR now.  But I am still in constant, chronic and severe pain, and some days I can't even shower I am weak enough still.  If I had the assistive devices I would function more independently and not be having to ask people to get or help with something.  Or lie awake and feel almost every stitch in the sheets, etc, because I have lost so much weight.

 Freaking

The newest product in the Lumex line of Specialty Healthcare Seating, the Preferred Care Bed-Recliner is a revolutionary product designed specifically for:

• Dialysis and Nocturnal Dialysis
• IV Therapy
• Oncology
• Cardiac Care
• Same Day Surgery
• Post-Operative Recovery
• Any Time Intensive
• Healthcare Procedures

The Lumex Preferred Care Bed-Recliner combines maximum patient comfort with ease of use by the caregiver. Unlike chairs converted into a “bed”, the Lumex Preferred Care Bed-Recliner offers the comfort of a true bed with an almost infinite number of seated/recline positions. A Specially designed Sleep Surface and Flexible Overlay provide proper support and extreme comfort in any position. Ultra Quiet DC Motors allow the Preferred Care Bed-Recliner to quickly move from a low position of 8.9" Deck Height to 30" Deck Height (without Sleep Support Surface and Overlay). This range of motion allows for easier care by the caregiver in the full up position and helps prevent patient injuries in the low position. The bed deck can be lowered to a height of 8.9" from the floor.

The positioning and height adjustment capability of the Preferred Care Bed-Recliner makes it ideal for patient transfer from a wheelchair, stretcher or another bed. The ability to have equipment at the same height helps to make patient transfers safer for both the patient and caregiver.

The almost infinite positioning capability of the Preferred Care Bed-Recliner makes it ideal for use as a cardiac chair for recovering cardiac patients who have heart and respiratory illnesses. The chair can be made to serve as a fully reclined bed when needed, but can also be adjusted to form a chair. This “cardiac position” helps to elevate the patient from the waist up, which provides relief to the lungs, increases circulation, and assists the patient in coming from a fully prone position to a sitting position without causing harm or undue strain. Unlike a hospital bed the Preferred Care Bed-Recliner is easier to adjust with separate adjustable sections that support back, bottom, arms, and legs rather than a single mattress which typically does not adjust fully into a chair/recline position.

The Sleep Surface and Lumex Overlay have been designed to maximize the comfort of the patient in all positions. Four corner straps secure the Elite Overlay to the Sleep Surface. The Sleep Surface is constructed of durable foam covered in Silvertex Fabric featuring SILVERGUARD Silver Ion Technology.

For maximum durability and infection control, the epoxy coated frame features SilverSolutions. Integrated directly into the finish, SilverSolutions kills more than 99.9% of odor and stain causing bacteria. Non-allergenic, safe for the environment and lasts for the expected life of the bed.

Key Features:

• Patient and Caregiver Pendants. Caregiver Pendant features a “lock-out” feature
• Lok-N-Roll Stability System, single step locking system allows the bed to be locked at any height
• Battery Assist in case of a power failure battery backup assists to power the basic functions of the bed
• Full and Reverse Trendelenburg Positions
• Infinite Positioning of Head and Foot Sections
• Adjustable Leg-Lift System to Improve Circulation
• No Pinch Points Within 200mm of Bed Perimeter
• Rolling Clearance of 20mm Over Thresholds
• Splash-Proof Electronics
• Under Bed Light

Warranty Information:

• Bed Frame: Limited Lifetime Warranty
• Welds: Limited 15 Year Warranty
• DC Electronic Components: Limited 3 Year Warranty
• Optional Head/Foot Boards: Limited 1 Year Warranty
• Sleep Surface & Overlay: Limited 2 Year Warranty

Available Upgrades and Options:

• Half-length Side Rails (pair) for head end or foot end of bed. Easily slides out of the way when not needed.
• Assist Bar - stable handhold assists with transfers in and out of bed and positioning.
• Wall Saver prevents head end of bed from touching the wall by maintaining minimum clearance. 

 For now; this would help:

MORE LIKE THIS TOO:

Looks low, usually I have to really prop them up-or my chest.

I HATE MY FUCKING LIFE!   Sorry: existance

 

NURSE MARY AND RSD SUCKS

NURSE MARY VISIT

WHERE I ENDED UP AFTER NURSE MARY

--------------------------PART TWO--------------------------------------------------(BELOW)---

--------------PART I----------------

Medical use of marijuana

Some doctors may recommend marijuana primarily for relief from the symptoms of disease rather than as a cure. Some of these conditions may include:

• Treatment for symptoms of AIDS
• Glaucoma 
• Neuropathy (diseases affecting the nerves or nerve cells) Ex. epilepsy
• Nausea and vomiting associated with cancer chemotherapy
• Pain caused by structural or psycho-physiological disorders
• Muscular spasticity and limb pain (multiple sclerosis or spinal cord injury)
• Symptoms of movement disorders such as Parkinson’s disease, Huntington’s disease, Tourette’s syndrome
• Appetite stimulant for diseases of malnutrition (cachexia or starvation)
• Nausea and vomiting (general) 
• Migraine headaches

A smokeless cannabis-vaporizing device delivers the same level of active therapeutic chemical and produces the same biological effect as smoking cannabis, but without the harmful toxins, according to University of California San Francisco researchers.

Have you ever wondered what temperature you should use for your vaporizer?

Δ-9-tetrahydrocannabinol (THC)
Properties: Euphoriant, Analgesic, Anti-inflammatory, Antioxidant, Antiemetic
Boiling point:  314.6 degree Fahrenheit

Δ-8-tetrahydrocannabinol (Δ-8-THC)
Properties: Resembles Δ-9-THC, Less psychoactive, More stable Antiemetic  

Boiling point:  347-352.4 degree Fahrenheit

Cannabinol CBD
Properties: Anxiolytic, Analgesic, Antipsychotic, Anti-inflammatory, Antioxidant, Antispasmodic
Boiling point: 1320-356 degree Fahrenheit

Cannabinol CBN
Properties: (Oxidation breakdown product) Sedative, Antibiotic
Boiling point:  365 degree Fahrenheit

Cannabichromene CBC
Properties: Anti-inflammatory, Antibiotic, Anti-fungal
Boiling point:  428 degree Fahrenheit